ANR fMEG OPM

Projet Home

MEG in fetuses (fMEG) and high-resolution electroencephalography (HR-EEG) have been developed at the fetal magnetoencephalography center in Tübingen and at Inserm 1105, Amiens, respectively, providing access to the abilities of the immature brain network from the last trimester of gestation in and ex utero. We will analyze with similar protocols the early development of the neuronal networks. Both spontaneous activity and event related cerebral responses to stimuli will be analysed by both approaches in and ex utero in Amiens and Tübingen. We will develop (1) Common paradigms for event related responses in MEG and HR-EEG. (2) Concurrent fMEG and HR-EEG, recordings in healthy prematures and fetuses of the same gestational age. (3) A dynamic estimator model from HR-EEG in premature to fMEG. (4) Adapt the tasks to the recordings performed in Amiens in fetuses and preterms with the new approach developed around the optically pumped magnetometer (OPM) by the Laboratoire d’Electronique et de Technologie de l’Information (CEA LETI), Grenoble. The complementary skills, HR-EEG in preterms in Amiens, fMEG in Tübingen and development of OPM in Grenoble, is a guarantee of success for this project.

Meet the team

Partners

GRAMFC, Université de Picardie Jules Verne

CEA LETI Grenoble/Lille,

  • Dr Etienne Labyt
  • Dr Matthieu LePrado
  • Dr. Agustin Palacios-Laloy,
  • Nicolas Miranda (IGR)
  • Mickael Alcaniz

fMEG Center at Eberhard Karls Universität Tübingen

  • Pr Hubert Preissl
  • Dr Katrin Sipple
  • Dr Lorenzo Semeia (Post Doc)
  • Dr Amer Zaylaa (Post Doc)

Publications

  1. Zahran.S, Mahmoudzadeh, M., Wallois, F., Betrouni, M., Derambure, P., Leprado, M., Palacios-Laloy , A., Labyt , E. Performance analysis of optically pumped 4He magnetometers vs conventional SQUIDs: from adult to infant head models, Sensor, 2022 Apr 18;22(8):3093.